Some aspects of experimental testing of seismic behavior of masonry walls and models of masonry buildings are discussed. In order to experimentally simulate the observed failure mechanisms and determine the parameters of seismic resistance, masonry walls of similar geometry and restraints as in the building’s structural system are tested by subjecting them to similar loading conditions as they are subjected to in a building during an earthquake. It has been shown that the test results depend on the shape and velocity of application of induced lateral load patterms used to simulate the seismic loading. Seismic behavior of masonry buildings can be studied by testing the small-scale models of buildings on simple earthquake simulators. However, since scale effects representadifficult problem to solve, the overall seismic behavior of structural systems only can most often be studied, and not the behavior of structural details.